Your genes, sleep, fruit flies, mice, and Palin

Despite the fact that she is a whiny, genuinely stupid quitter, Sarah Palin has been popping up all over the place lately. Most recently she has been spouting off some garbage that Obama wants to set up a “death panel” in the health care bill. In truth, the bill calls for discussing one’s living will (and related concerns) with a doctor, should one choose to do that. This serves to better protect the interests of the patient. Such a measure could have avoided that whole Terri Schiavo fiasco. But, again, Palin is genuinely stupid. She never knows what’s going on. She makes this clear – literally – every single time she publicly speaks. She was especially clear when she said some remarkably stupid things about fruit fly research during the campaign season. I mention all this because of some recent research which relied on fruit flies*, and which can have a direct impact on the health of people.

Scientists have discovered the first gene involved in regulating the optimal length of human sleep, offering a window into a key aspect of slumber, an enigmatic phenomenon that is critical to human physical and mental health.

The article is well worth the read, and will probably give a fuller picture than I’m going to give. It’s all about a gene which has some seemingly minor variations, yet these variations (alleles) can drastically affect the health of the carrier.

The researchers found that mutated versions of the gene can affect the time some people go to bed, wake up, and how well they physically, emotionally, and mentally perform throughout the day. For instance, most people need roughly 8 hours of sleep a night, but one gene variant allows some to get back on 6 hours while not experiencing adverse consequences to their health.

And of course, this research was possible due to the contributions of various mice and fruit flies. When researchers would find a particular variant of this gene, they would ‘tinker’ with the same gene in these test subjects and measure the effects. One finding was that genetically engineered mice would compensate far less for sleep deprivation than would the control mice.

It isn’t clear yet exactly what it is about this gene (DEC2) which triggers the change in sleep need, but it may be that it makes protein transcription weaker, but other explanations are possible until more research is done.

*What genetic research doesn’t rely on fruit flies these days?

Catching Conservapedia in a lie again

From their lying front page:

Another new paper was just published in Journal of Climate. Added proof Al Gore & Company are simply lying hucksters, out for a buck. Written by eminent climatologists, called Greenland Ice Sheet Surface Air Temperature Variability: 1840–2007 which discusses data from Greenland since 1840. No unprecedented recent warming is found. For example, they find that the 1919-1932 warming was 1.33 times greater than the 1994-2007 “warming”. [19] The new report mirrors one from the United States Senate back in 2007. [20]

Just like the last time, they make the mistake of linking to the abstract they reference.

Thus, it is expected that the ice sheet melt rates and mass deficit will continue to grow in the early twenty-first century as Greenland’s climate catches up with the Northern Hemisphere warming trend and the Arctic climate warms according to global climate model predictions.

These people are kooks.

Catching Conservapedia in a lie again

From their lying front page:

Another new paper was just published in Journal of Climate. Added proof Al Gore & Company are simply lying hucksters, out for a buck. Written by eminent climatologists, called Greenland Ice Sheet Surface Air Temperature Variability: 1840–2007 which discusses data from Greenland since 1840. No unprecedented recent warming is found. For example, they find that the 1919-1932 warming was 1.33 times greater than the 1994-2007 “warming”. [19] The new report mirrors one from the United States Senate back in 2007. [20]

Just like the last time, they make the mistake of linking to the abstract they reference.

Thus, it is expected that the ice sheet melt rates and mass deficit will continue to grow in the early twenty-first century as Greenland’s climate catches up with the Northern Hemisphere warming trend and the Arctic climate warms according to global climate model predictions.

These people are kooks.

Thought of the day

These don’t even look real

These don't even look real

Abusing science

Conservapedia is back to abusing science. This is from their “news” section.

The study, which was published on July 14, 2009 in the peer-reviewed journal Nature Geoscience, found CO2 was not to blame for a major ancient global warming period and instead found “unknown processes accounted for much of warming in the ancient hot spell.” The press release for the study was headlined: “Global warming: Our best guess is likely wrong.”

“In a nutshell, theoretical models cannot explain what we observe in the geological record,” said oceanographer Gerald Dickens, a co-author of the study and professor of Earth science at Rice University. “There appears to be something fundamentally wrong with the way temperature and carbon are linked in climate models.”

The mistake Conservapedia made is so readily linking to the abstract.

We conclude that in addition to direct CO2 forcing, other processes and/or feedbacks that are hitherto unknown must have caused a substantial portion of the warming during the Palaeocene–Eocene Thermal Maximum. Once these processes have been identified, their potential effect on future climate change needs to be taken into account.

While the idiots over at Dumbopedia (good one, right?) are claiming that this study PROVES!!! that global warming is not man-made (thus implying that any polluting business practice is a-okay), the study is saying no such thing. This is referencing a period of warming where CO2 alone does not account for all the warming. That isn’t to say that the rise in CO2 can be dismissed during that time – nor is it saying anything about our time. It’d be like saying natural selection doesn’t account for all the change in evolution, therefore evolution is false. CO2 still was a huge factor by which warming was initiated (upwards of 38 degrees F). Today it remains a huge factor.

Let’s just say it. Conservatives are not concerned about science. They care about allowing businesses to practice as they please. That’s it.

A Short History of Nearly Everything

I am currently in my fourth and a half listening of the audio version of Bill Bryson’s “A Short History of Nearly Everything“. It’s about 6 years old, but I’ve only recently been introduced to it. I’ve been severely missing out.

This is an overwhelmingly encompassing account of, well, nearly everything. Bryson goes through, with engrossing detail, the history of science. He begins with, naturally, the Big Bang and much of physics. From there he jumps to just about every topic (in an order I cannot recall), from chemistry to biology to geology to mathematics to astronomy. He gives a set of Britannica Encyclopedias’ account of so many scientists, what they were thinking, why they were thinking it, and why they were right or wrong or on the right track or distracted or petty or prideful or anything of which I would never think to ask or consider. This is the best science book I have ever heard or read, and it isn’t even specific like, say, The Selfish Gene (which was also excellent).

One of the best things about this audio book is Bryson’s voice. It’s soothing. It’s also not boring. As much as I love The Science Channel and all the science shows I can find, I have come to the conclusion that I can only watch these if I’m wide awake. It isn’t that the topics are boring. The presentation is usually just very monotone. (One notable exception is the Discovery Channel’s Walking With Cavemen narrated by Alec Baldwin.) Bryson’s book suffers from no such calamity.

Get this book, preferably the audio version (though I’m sure the text version is equally fantastic).

Bats

We’ve had an abundance of rain in the past month in my area. As such, we have a lot of standing water. To make matters worse, I live near a lake, which often means there’s standing water nearby anyway (and that’s definitely the case here). This all adds up to mean a deluge of mosquitoes. Fortunately, there are also a lot of bats around here. But it isn’t all gum drops and soda. Sometimes having a lot of something means things will start showing up where you don’t want them to show up.

In the past two days, I’ve encountered three bats in my apartment. The first was dead. I’m not sure if a cat killed it or if it died naturally or if it was white nose syndrome (though there was no visible fungus). The second was among a series of shirts I have layed over a large change bottle. I got that guy downstairs before he decided to take a quick aerial tour of the area. I eventually got him out the door. The third one, which showed up tonight, almost victimized by the hungry mouths of several cats, decided to go for the extended stay with optional aerial tour of the living room. It was fascinating watching it flying back and forth and back and forth and back and forth. After waking some sleeping roommates, we got it sequestered in the sun room/porch. Unfortunately, there’s no light in that small room, so there was a lot of fast ducking and thrown blankets in response to the constant dives and erratic motions of the bat. With time and a little help from an empty Yahtzee box, we got it out one of the windows.

So, in honor of this story (which I don’t think is over – we have little idea of where these things are originating), I am reposting some bits from a Carl Zimmer piece on bats. Be sure to click “Bat in wind tunnel” and “Vampires running!” to watch the videos. For whatever reason, I cannot embed any better than that.

Bats evolved about 50 million years ago from squirrel-like ancestors. They probably made their first forays into the air as gliders. Like living gliders, they used flaps of skin to increase their surface area, letting them glide further. Their hands evolved long spindly fingers that were joined by membranes. Some early bat fossils suggest that they may have shifted from gliding to alternating between gliding and bursts of fluttering. Eventually bats evolved sustained powered flight.

Bats evolved a way to take advantage of the same laws of physics birds use to fly. And many scientists who have studied bat flight in the past have basically treated bats like leathery birds. Yet there’s no reason to assume that this should be so. After all, it would not be surprising to find that the way the feathers on a bird’s wing react to air pushing against them are different from the way the stretchy membranes on a bat react. Birds don’t have wing surfaces connecting their front and back legs, like bats do. And while birds only have a couple joints in their wing skeleton, such as at the elbow and wrists, bats have lots of knuckles they could, in theory, bend selectively to alter their wing surface. Bats also have lots of sensitive hair cells on their wings that appear to track the speed and direction of the air flow, and the information they get from the hairs may help them make fine adjustments to their wings many times a second.

Bat in wind tunnel from Carl Zimmer on Vimeo.

I think the creepiest thing about this whole event, other than the possible rabies, was the way I watched the third bat walk. It landed on the floor a couple times and crawled around a bit. I wish I could have had more light to really observe it.

Vampire running! from Carl Zimmer on Vimeo.

DNA Portrait