400lbs man completes marathon

“I’d like to see the Kenyan improve his marathon time by two hours,” he joked.

That’s what Kelly Gneiting said after completing the second marathon of his life in nearly 10 hours of jogging and walking. Normally that would be a terrible time, but considering that the guy is a 400lbs sumo wrestler, I would say that’s pretty good.

I can’t say I’ve ever had a goal of running a marathon, but several of my Kilimanjaro group members were and are active runners, completing various running thing-a-ma-jigs. One of them, Jim Hodgson, even used to be a pretty big guy 10 years ago. Now he completes marathons and Ironman competitions fairly regularly, throwing in the occasional hike up massive boobs. It’s an inspiration, even to a skinny guy. I’m still not going to be in the Boston Marathon anytime soon, but I am going to make it my goal to run at least 10 miles straight by the end of the summer, with an ultimate goal of 15.

If a 400lbs guy can do it, so can I.

Revelation TV interview of Richard Dawkins

My two favorite parts happen between 36 and 40 minutes. First,

Conder: Am I just deluded?

Dawkins: Probably, yes.

Second, shortly thereafter Conder cites the fulfillment of prophecies, especially those that come from Micah, as one of his big reasons for initially being attracted to the Bible. It’s hilarious. As I’m sure all good Christians know, the gospels were often poor attempts to fulfill those prophecies. That’s the case with the birth of Jesus.

Anyway. The interviewer is pretty awful, but Dawkins’ parts are good.

Happy spring

Thought of the day

In other news, at the report of war, President Obama’s poll numbers soared among Republicans.

Supermoon tonight

According to every other Facebook status update – and this news article – the moon is at its closest point to Earth in 18 years. The best time to see it? Probably when the sun set. But since no one has a time machine yet, the best time is right meow. Go.

Tarantula Nebula

Want Jesus out of government?

A Jewish lawmaker form Minnesota wants to take Jesus out of legislative sessions. Great, right? Not quite.

A Jewish Minnesota lawmaker is asking Senate leaders to allow only nondenominational prayers to open sessions, after feeling “highly uncomfortable” when a Baptist pastor repeatedly mentioned Jesus Christ and Christianity in one of the invocations.

Democratic Sen. Terri Bonoff says she wants Republican Senate Majority Leader Amy Koch to change the letter submitted to all visiting chaplains to say they are “required,” rather than “requested,” to make prayers nondenominational.

“I’m a very religious woman and believe deeply in God,” said Bonoff, of the Minneapolis suburb of Minnetonka. “We honor God in public and our political discourse, and that’s proper. But in doing a nondenominational prayer we are honoring him without violating the separation of church and state.”

Uh-huh. It’s not okay to prayer to Jesus because it makes people uncomfortable. But praying to God? Why, that’s just dandy. Who could that possibly offend? What part of the constitution could that possibly violate?

Bonoff is obviously a mental midget, but she still may be able to win this battle. She just needs to look at the system itself.

Koch said Wednesday she wouldn’t support such a requirement. She said the Senate invites leaders from numerous Christian and non-Christian faith traditions to pray, and notifies them that senators come from a diverse background. “I’m not going to get into the process of sort of editing prayer,” Koch said.

If senators can invite leaders from all sorts of organizations, Bonoff ought to invite an atheist leader. It’s Minnesota, get PZ Myers. Or any other atheist. It doesn’t matter. As long as the person proudly wears the label of “atheist”, all these Republican mooks will immediately start backtracking. Get the person to appear over and over; don’t let anyone think it’s just a one-time thing. Show the anti-constitutional Republicans that if they want to violate the separation of church and state by using government resources to promote religion, then they’re going to have to deal with the consequences of promoting views they don’t like. (Actually, the “consequences” would probably be very good, but I’m biased with my positive views of reason and rationality.)

Thought of the day

It amazes me how the first run of (almost) spring is both the best and worst run of my life. Every year.

How penicillin works

I’m currently in the midst of a short break I’m taking whilst studying for a massive microbio test I have in a few hours. And what better way to take a break than to post about one of the essay questions I know will be on the exam?

β-lactam antibiotics include penicillin and cephalosporins. (Everything that follows applies to both, but most people seem to be more interested if the topic is the more familiar penicillin subgroup.) The way these antibiotic works is by attacking the cell walls of bacteria. This makes gram-positive bacteria more susceptible than gram-negative bacteria; gram-positive bacteria have an outer peptidoglycan layer whereas gram-negative bacteria have their peptidoglycan layer between a plasma-membrane layer and an LPS layer. (No, I’m not going to define all these terms I’m using.)

Transpeptidase molecules are necessary for catalyzing cross-linking of glycan-linked peptide chains. Penicillin, all coy and sneaky, causes transpeptidase to link to it (penicillin) instead. (Transpeptidases are known as penicillin-binding proteins, or PBPs. I find the name misleading since it sounds like their purpose is to get all buddy-buddy with penicillin.) This prevents cross-linking. As I’m sure every nerd knows, cross-linking is what gives the peptidoglycan outer wall much of its strength. So while cell wall synthesis continues unabated, no cross-linking is happening, thus weakening structural integrity. Mike Holmes would be pissed if he was a biologist and he saw this happening. (Come on, HGTV fans, I know you’re out there.) Furthermore, autolysins are being released. What this means is the gram-positive bacteria has a weak and self-degrading outer wall. Osmotic pressure eventually causes lysis.

Now please excuse me while I enter hour 6 of studying for the (literally) 109 other things I need to know for my upcoming test.

Happy St. Patrick’s Day