The Republican Party hates the idea of progress.
Filed under: Misc | Tagged: Republicans, Thought of the day | 3 Comments »
The Republican Party hates the idea of progress.
Filed under: Misc | Tagged: Republicans, Thought of the day | 3 Comments »
I currently have plans in the works to hike Mount Kilimanjaro in Tanzania. I’m aiming for late June as the rainy season will be over and there is a full moon on the 26th. However, I’m having trouble making sure I can find a reputable guide company. I met a hiker out on the AT last summer who used Good Earth Tours and he said his trip was successful, but what I didn’t ask was how the porters were treated. Some of these companies make their porters sleep in terrible conditions without proper gear or even the same meals the clients will be having. They even pay them half the recommended minimum daily wage sometimes. I don’t want one of those companies.
Right now I’m checking out Ultimate Kilimanjaro because it is an American based company. I’m weary, however, of these companies that charge upwards of $2000 less than other places I’ve seen. I obviously don’t want to overpay for the sake of faux comfort and unnecessary luxuries, but I also don’t want to employ a bunch of people who are bitter over their low pay and thus not really concerned with my hiking experience.
So that’s where my small blog following comes in. Does anyone have any experience with any Kilimanjaro companies? Any friends with experience? If so, please give me all the information you can.
Filed under: Hiking | Tagged: Good Earth Tours, Hiking, Mount Kilimnajaro, Tanzania, Ultimate Kilimanjaro | 3 Comments »
Apparently there’s this low-budget, no-name movie floating around at these unheard of giant theaters. I think it’s called Avatar and it’s playing at an IMAX.
Be jealous.
Filed under: Misc | Tagged: Avatar, IMAX, Thought of the day | Leave a comment »
Rush Limbaugh recently said this:
Everything this president sees is a political opportunity, including Haiti, and he will use it to burnish his credentials with minorities in this country and around the world, and to accuse Republicans of having no compassion.
So what does Rush want? Should Obama not help Haiti? Was George Bush right when he initially only offered $35 million in aid after the 2004 tsunami? Perhaps he should have given less?
The reason anyone might accuse Republicans of having no compassion is because Limbaugh is the unofficial icon of the party and he says garbage like this. If he doesn’t like being perceived as heartless, then he needs to stop being heartless. It’s pretty simple.
He also appeared to discourage help for the island nation, saying, “We’ve already donated to Haiti. It’s called the U.S. income tax.”
So don’t give any more, people! What Obama has donated so far counts as your contribution! Idjit. 
Text “HAITI” to 90999 to automatically donate $10 to the Red Cross.
Filed under: News | Tagged: Haiti, Obama, Rush Limbaugh | Leave a comment »
I recently got an email from an irate reader concerning something I wrote about naturopathy. She sent her letter to the address I have set up for my paper, Without Apology, but I never printed anything of relevance in there. She also did not specify which piece of writing she was referencing. I’ve actually written several posts about naturopathic ‘medicine’. Probably the one with the toughest language, however, was this one. There I called Christopher Maloney, local naturopathic ‘doctor’, a charlatan, mountebank, and quack. All those terms were supported by clear refutations and short examinations of the lies Maloney was peddling. I can’t be sure if that’s what set off the reader, but here’s what she had to say.
Dear Michael Hawkins,
I am writing you a friendly letter to let you know that you might want to write an apology to Dr. Maloney for your article. I don’t think you really educated yourself on his medical education. And unfortunately for you, his wife is a lawyer. What you wrote is slander, and you definitely might be in a allot of trouble. Fact, he is a Naturopathic Doctor. People actually travel all over the country just to get an appointment to see him. But did you know you have to be a DO. or an MD. Oh, from your article it sounds like you might not know allot about the medical field. This type of doctor goes to medical school and study’s more osteopathic type of medicine. Thiers even a highly credited school in Maine called UNE :). And then you have an MD :) which is the one your probably more familiar with. Both study’s require at least 10 yrs. of medical schooling. Now a Homeopathic Doctor, or Naturopathic Doctor has to become a DO, or an MD before their aloud to study Naturopathic, or Homeopathic medicine. Which is usually an additional 2-4 yrs. of additional medicine. So yes, Dr. Maloney has been to over 12yrs. of medical school. And when he feels necessary, he will prescribe traditional medicine as you call it. But most of the time he try’s to heal threw more natural means because most people heal quicker threw natural means :). So a little bit more about him……. He went to Harvard, yup the big school of medicine LOL, and Brown LOL so he pretty smart and extremely educated. So yes, be careful before you put something in print OK :). The article made you look very silly :)
Wishing You The Best,
Cheryl :)
My favorite part is that after the threats and insults, she wishes me ‘the best’. No, really.
It’s perplexing that Cheryl has chosen to focus on Maloney’s medical education. I never raised that as an issue. I mean, creationists have completed bio programs from Harvard; that doesn’t mean I’m about to defer to them. But, at the least, she’s inaccurate. He did go to Harvard, but I see nothing about Brown. Also, notice the information Maloney includes as part of his education.
* B.A. Swarthmore College, Swarthmore, Pennsylvania
* Diploma in Continuing Health Studies, Harvard University, Cambridge, Massachusetts.
* Four year medical degree from National College of Naturopathic Medicine, Portland,Oregon.
* National science boards and clinical medicine boards.
* Year in Singapore and Malaysia studying medicine with homeopaths, naturopaths, and osteopaths as well as traditional Chinese healers.
* Licensed in the state of Maine as a naturopathic doctor.
First, noticed nothing about Brown. Second, I reject the overall legitimacy of naturopathic schools, even if they do manage to get accredited. Maloney’s school, for instance, teaches Classical Chinese medicine. What does that include, you ask?
Cupping: A type of Chinese massage, cupping consists of placing several glass “cups” (open spheres) on the body. A match is lit and placed inside the cup and then removed before placing the cup against the skin. The resulting effect is the burning of oxygen within the cup, creating a relative vacuum, that allows the cup to stick right to the skin via suction. When combined with massage oil, the cups can be slid around the back, offering what can only be thought of as a reverse-pressure massage.
And third, notice that two of the final three things Maloney lists are not parts of his education, but rather his C.V. And need I say anything of studying cupping and similar exercises with Malaysian homeopaths?
In the process of making this post I’ve noticed a second email. This one is from a J. Smith. It’s clear he’s referring to the letter I had published in the local paper. It’s also clear that he had a bit more to get off his chest. I’m not going to take the time (at least right now) to respond to all he’s had to say, but I will paste his email in the comment section of this post.
Correction: I did sort of bring up Maloney’s education when I spoke of his qualifications. But again, this goes back to the creationist analogy. A person can have a bio degree, but if he believes in instant creation, he’s unqualified to tell me anything about evolution.
Also, I had forgotten the email for Without Apology was listed under my letter to the editor.
Filed under: Pure bullshit | Tagged: Christopher Maloney, Naturopathic medicine, Naturopathy | 4 Comments »
As probably everyone knows, a terrible Earthquake rocked Haiti recently. The estimates for the death toll are highly varied this early on, but I’ve so far read numbers ranging from 100,000 to 500,000. It’s possible this could be worse than the 2004 tsunami that killed roughly 230,000 people (though I doubt the economic damage will be worse given Haiti’s deep poverty). Haiti has a population just under 10 million. That means there’s a loss likely between 1-5% of the population. That would be 3 to 15 million people being wiped out in the U.S., not to mention the massive swath of individuals displaced.
As one might imagine, aid is greatly needed. There are a ton of avenues for making donations, but one of the easiest is through the Red Cross. Texting “HAITI” to 90999 will donate exactly $10.
Filed under: News | Tagged: 90999, Earthquake, Haiti, Red Cross | 1 Comment »
The NFL should fine officials when they go crooked. Simple as that.
Filed under: sports | Tagged: Alex Burrows, Hockey, NHL, Stephane Auger | Leave a comment »
There isn’t a god, but if there was one, he probably wouldn’t care about your sex life.
Filed under: Misc | Tagged: Sex! Sex! Sex!, Thought of the day | 1 Comment »
Psychology is far from my primary interest in science, but I was fortunate enough to come by a story on negative thinking that I found highly interesting. There’s a lot of stuff out there that goes contrary to our intuition but ultimately makes logical sense.
Here’s how [John] Cloud explains the psychology of Hayes and like minds:
Hayes and other third wavers say trying to correct negative thoughts can, paradoxically, intensify them, in the same way that a dieter who keeps telling himself “I really don’t want the pizza” ends up obsessing about … pizza. Rather, Hayes and the roughly 12,000 students and professionals who have been trained in his formal psychotherapy, which is called acceptance and commitment therapy (ACT), say we should acknowledge that negative thoughts recur throughout life. Instead of challenging them, Hayes says, we should concentrate on identifying and committing to our values. Once we become willing to feel negative emotions, he argues, we will find it easier to figure out what life should be about and get on with it. That’s easier said than done, of course, but his point is that it’s hard to think about the big things when we’re trying so hard to regulate our thinking.
Filed under: Science | Tagged: John Cloud, Joshua Shenk, Negative thinking, Positive thinking, Psychology, Stephen Hayes, Therese Borchard | Leave a comment »
If there’s one phrase that has framed virtually all my education in biology the best, it would be “It’s all about shape.”
Probably the easiest way to think about this is with an analogy of a key and a keyhole. That’s how biological and chemical interactions occur – one thing fits into another. And so that’s the case with what researchers have done with the restoration of the activity of a particular enzyme.
The enzyme, called ALDH2, plays an important role in metabolizing alcohol and other toxins, including those created by a lack of oxygen in the wake of a heart attack. It also is involved in the metabolism of nitroglycerin, which is used to prevent chest pain (angina) caused by restricted blood flow and oxygen to the heart.
The problem is that a lot of people have a mutation in the gene which codes for this enzyme. This presents a couple of options. One is gene therapy where, in effect, a small piece of the genome (just a single gene) is altered, usually using an adeno-associated virus to introduce the correct DNA sequence into a nucleus (as happened with the spider monkeys recently cured of color blindness). This presents some problems because there isn’t a one-to-one correspondence with genes and proteins or enzymes. Alternative splicing means that a single gene can code for several different proteins. Sure, a correction may be just right for making one correct protein, but it may not also be correct for other proteins. This can result in serious side effects (though it didn’t in the spider monkeys). There are other reasons gene therapy can go awry, too, so it isn’t necessarily the best choice, however promising the field is for curing innumerable afflictions.
Then there’s the option these researchers took. Instead of messing around with anything to do with the genome, they looked at the proteome. Specifically, they looked at the enzyme ALDH2. Its mutated form doesn’t perform very well. It still works because it maintains some of its shape, but its active site does not comport to the appropriate substrates of the other molecules its trying to act upon as well as it should. So in effect, researchers took a compound (Alda-1) and injected into test subjects. In turn, this compound altered the shape of ALDH2, putting it back in proper working form.
“Because of the mutation in the gene, parts of the protein structure become loose and floppy. Alda-1 reactivates the enzyme by propping up those parts of the structure so they regain normal function,” said Dr. Hurley, director of the Center for Structural Biology on the Indiana University-Purdue University Indianapolis campus.
It’s an elegantly simple idea with a complex execution.
Incidentally, this all can be related to evolution in that if an enzyme has a given shape which catalyzes something even a little, it can be sculpted by natural selection to better catalyze that reaction, eventually getting to a relative optimum in shape.
Filed under: Science | Tagged: Alda-1, ALDH2, Center for Structural Biology on the Indiana University-Purdue University Indianapolis campus., Daria Mochly-Rosen, Nature Structural Biology, Thomas Hurley | 1 Comment »